Dear all,
We would like to invite you to the 98th Global NMR meeting on Tuesday, March 11th, featuring Professor Chad Rienstra of the University of Wisconsin, US.
Title: Magic-Angle Spinning Probes for High and Ultra-High Fields
Abstract: In this talk, I will describe recent progress in the development of custom-designed probes for magic-angle spinning solid-state NMR at 600, 750, 900 and 1100 MHz, including versions with improved sensitivity for 13C and 1H detection and applications to biological macromolecules including microcrystals, fibrils, membrane proteins and RNAs.
Speaker’s Biography:
Chad Rienstra is the Evelyn M. Mercer Professor of Biochemistry and Co-Director of the National Magnetic Resonance Facility at Madison (NMRFAM) at the University of Wisconsin-Madison. He leads the NMRFAM technology development program in solid-state NMR, including the design and application of magic-angle spinning (MAS) probes for improving the spectra of challenging biological assemblies such as fibrils, membrane proteins, enzymes, and drug complexes. His group solved the first structures of alpha-synuclein fibrils and the active form of amphotericin B in complex with ergosterol, respectively leading to clinical candidates for Parkinson disease diagnosis and antifungal therapy. As a co-investigator for the Network for Advanced NMR, he has led the recent installation of a 1.1 GHz spectrometer at NMRFAM, including custom MAS probes that deliver high homogeneity and stability for optimal resolution and sensitivity in long-term biological experiments.
Webinar Details:
Time: Tuesday, March 11th, 11:00 AM Boston/ 5:00 PM Paris/ 9:30 PM Delhi
Link: https://nyu.zoom.us/j/91419770855
Best Regards,
Global NMR Discussion Meetings